This virus can affect all systems of the body and its symptoms vary from a simple upper respiratory infection bacterial co-infection is another problem in COVID-19 which affects the prognosis of patients. pandemic, various approaches and therapeutics were introduced for treating COVID-19 patients. are not helpful enough, especially for complicated cases. Therefore, the therapeutic benefits of mesenchymal stem cells, especially their antimicrobial activity, will help us understand how to treat COVID-19. Herein, mesenchymal stem cells may stop the immune system from becoming overactive in COVID-19 patients.

This meta-analysis revealed that the PBMT utilizes beneficial anti-inflammatory effects and modulation of the immune system on lung damage in animal models and clinical studies. However, animal models and clinical studies appear limited considering the evidence’s .quality; therefore, large clinical trials are still required