Onion Extract on Cell Gene Expression Profile: a System Biology Approach

https://ctrmrc.tums.ac.ir//article/Onion-Extract-on-Cell-Gene-Expression-Profile:-a-System-Biology-Approach

Assessment of molecular mechanism of yellow onion extract on cell line Caco-2 was the aim of this study. The gene expression profiles of Caco-2 cells in the presence of yellow onion extract versus control cells were analyzed via GOE2R software. The significant differentially expressed genes (DEGs) were assessed via network analysis and the central nodes were enriched via gene ontology. Results Thirteen central nodes including JUN, ATF3, DUSP1 VEGF, CDKN1A, SNAI1, HSPB1, MCL1, SQSTM1, SREBF1, MAP