Activation of CDKN2A and Up-regulation of PETN Are Key Features of Sunscreen Usage Versus Light Irradiation

https://ctrmrc.tums.ac.ir//مقالات-علمی/Activation-of-CDKN2A-and-Up–regulation-of-PETN-Are-Key-Features-of-Sunscreen-Usage-Versus-Light-Irradiation-

Abstract Introduction Sunscreen plays an unexpected role in protecting the skin against the harmful effects of sunlight. Skin protection against UV rays is highlighted as the main property of sunscreen. The present study investigated the core part of the molecular mechanism of skin protection by sunscreen. Methods Gene expression changes of the irradiated human skin with sunlight in the presence of sunscreen were mined from the Gene Expression Omnibus (GEO) database and analyzed to find the sign