Propolis is a natural product of honey bees that is characterized by therapeutic effects on diverse diseases. To elucidate the molecular mechanism of propolis effects on tumor, protein-protein interaction (PPI) network analysis of proteome data of Hep-2 cells treated with red propolis was conducted.

Background: Inflammation is a double-edged sword in the pathophysiology of chronic diseases, such as type 2 diabetes mellitus (T2DM). The global rise in the prevalence of T2DM in one hand, and poor disease control with currently-available treatments on the other hand, along with an increased tendency towards the use of natural products make scientists seek herbal medicines for the management of diabetes and its complications by reducing C-reactive protein (CRP) as an inflammatory marker.

Introduction: It is reported that migraine may be a risk factor for brain cancers. Since one of the best ways to assess this possible relationship is to study the molecular mechanism, here the common central dysregulated proteins between these diseases are investigated via network analysis.

Aim: Determining critical dysregulated proteins in liver cancer was the main aim of this study

Purpose: The study aim was to evaluate the effects of public lockdown during the covid-19 pandemic on glucose and metabolic parameters as well as body weight control in type 2 diabetic patients.

cutaneous wound is caused by various injuries in the skin, which can be wrapped with an efficient dressing. Electrospinning is a straightforward adjustable technique that quickly and continuously generates nanofibrous wound dressings containing antibacterial and anti-inflammatory agents to promote wound healing.

Acute myeloid leukemia (AML) is a malignant disorder characterized by a poor prognosis. Current therapeutic approaches include chemotherapy, steroids administration, and blood transfusion.

Background and objectives: Coffee is a favorable drink in the world with advantages that are documented during different investigations. In the present study, the effect of caffeine which is one of the important compounds of coffee has been evaluated on function of mice liver via network analysis and gene ontology enrichment.

Introduction: For cell-based therapies of lung injury, several cell sources have been extensively studied. However, the potential of human fetal respiratory cells has not been systematically explored for this purpose. Here, we hypothesize that these cells could be one of the top sources and hence, we extensively updated the definition of their phenotype.

Purpose: This study aimed to compare individual pharmacokinetic (PK) parameters of vancomycin with predicted values from five population PK models in patients with diabetic foot infections (DFIs)