مقالات انگلیسی
https://ctrmrc.tums.ac.ir//article/صفحه:1
لیست اخبار صفحه 1 Mitogen-Activated Protein Kinase-3 (MAPK3) Is the Main Target of Microsecond Pulsed Electric Field in Human Medulloblastoma Mitogen-Activated Protein Kinase-3 (MAPK3) Is the Main Target of Microsecond Pulsed Electric Field in Human Medulloblastoma 1405/07/05 - Introduction Pulsed electric fields (PEFs) are applied to facilitate the transfer of various types of molecules, such as pharmaceuticals, into living cells. In the present study effect of microsecond PEF on human medullob
مقالات علمی
https://ctrmrc.tums.ac.ir//مقالات-علمی/صفحه:5
لیست لیست اخبار صفحه 5 Antioxidative hypoglycemic herbal medicines with in vivo and in vitro activity against C-reactive protein Antioxidative hypoglycemic herbal medicines with in vivo and in vitro activity against C-reactive protein; a systematic review 1402/07/09 - Cancer Chemo-Preventive Effects of Red Propolis a System Biology Approach Cancer Chemo-Preventive Effects of Red Propolis a System Biology Approach 1402/07/08 - Results The results implied that six hub-bottlenecks including ACTB, G
Activation of CDKN2A and Up-regulation of PETN Are Key Features of Sunscreen Usage Versus Light Irradiation
https://ctrmrc.tums.ac.ir//مقالات-علمی/Activation-of-CDKN2A-and-Up–regulation-of-PETN-Are-Key-Features-of-Sunscreen-Usage-Versus-Light-Irradiation-
Abstract Introduction Sunscreen plays an unexpected role in protecting the skin against the harmful effects of sunlight. Skin protection against UV rays is highlighted as the main property of sunscreen. The present study investigated the core part of the molecular mechanism of skin protection by sunscreen. Methods Gene expression changes of the irradiated human skin with sunlight in the presence of sunscreen were mined from the Gene Expression Omnibus (GEO) database and analyzed to find the sign
Bridging the Gap Between Bone Marrow Transplantation and CAR-T Cell Therapy in Hematological Cancers
https://ctrmrc.tums.ac.ir//article/Bridging-the-Gap-Between-Bone-Marrow-Transplantation-and-CAR–T-Cell-Therapy-in-Hematological-Cancers
one marrow transplantation and chimeric antigen receptor T cell therapy have become two important treatment modalities for hematological malignancies, each having different mechanisms of action and therapeutic roles. Abstract Bone marrow transplantation and chimeric antigen receptor T cell therapy have become two important treatment modalities for hematological malignancies, each having different mechanisms of action and therapeutic roles. This chapter focuses on the chronological development an
GMP-Based Isolation of Full-Term Human Placenta-Derived NK Cells for CAR-NK Cell Therapy in Malignant Melanoma
https://ctrmrc.tums.ac.ir//article/GMP–Based-Isolation-of-Full–Term-Human-Placenta–Derived-NK-Cells-for-CAR–NK-Cell-Therapy-in-Malignant-Melanoma
Melanoma, a severe type of skin cancer, poses significant management challenges due to its resistance to available treatments. Despite this obstacle, the high immunogenicity of melanoma renders it amenable to immune therapy, and NK cells have been identified as possessing anti-tumor properties in immunotherapy. Abstract Melanoma, a severe type of skin cancer, poses significant management challenges due to its resistance to available treatments. Despite this obstacle, the high immunogenicity of m
سلاح کوچک ضدسرطان
https://ctrmrc.tums.ac.ir//news/سلاح-کوچک-ضدسرطان
در مقاله‌ای که اخیرا در مجله Science Advances منتشر شد، محققان توضیح دادند که چگونه از sEVهای (وزیکول های خارج سلولی کوچک)مهندسی‌شده در آزمایشگاه برای هدف‌گیری گیرنده سطح سلول DR5 (واسطه مرگ و التهاب در بسیاری از انواع سلول‌ها) استفاده کرده‌اند؛ گیرنده‌ای که در بسیاری از سلول‌های توموری یافت می‌شود. فعال شدن DR5 می‌تواند فرآیند خود‌تخریبی آپوپتوز را در سلول‌ها آغاز کند. با اینکه تلاش‌های ۲۰ سال گذشته برای توسعه درمان‌های موفقی که DR5 را هدف قرار دهند، نتیجه‌بخش نبوده، این روش جدید با استفاده از
Introducing Critical Genes in Response to Photodynamic Therapy: A Network Analysis
https://ctrmrc.tums.ac.ir//مقالات-علمی/Introducing-Critical-Genes-in-Response-to-Photodynamic-Therapy:-A-Network-Analysis
Photodynamic therapy (PDT) is applied as an efficient method for preventing the progress of cancers. Light and a photosensitive compound which is known as photosensitizer (PS) are the main parts of PDT. Abstract Introduction Photodynamic therapy (PDT) is applied as an efficient method for preventing the progress of cancers. Light and a photosensitive compound which is known as photosensitizer (PS) are the main parts of PDT. In the present study, molecular events after using PDT in the presence o
Cancer Chemo-Preventive Effects of Red Propolis: a System Biology Approach
https://ctrmrc.tums.ac.ir//مقالات علمی/Cancer-Chemo–Preventive-Effects-of-Red-Propolis:-a-System-Biology-Approach
Propolis is a natural product of honey bees that is characterized by therapeutic effects on diverse diseases. To elucidate the molecular mechanism of propolis effects on tumor, protein-protein interaction (PPI) network analysis of proteome data of Hep-2 cells treated with red propolis was conducted. Abstract Background and objectives Propolis is a natural product of honey bees that is characterized by therapeutic effects on diverse diseases. To elucidate the molecular mechanism of propolis effec
Introducing Albumin and Interleukin 6 as Common Critical Dysregulated Proteins Between Migraine and Gliosarcoma
https://ctrmrc.tums.ac.ir//مقالات علمی/Introducing-Albumin-and-Interleukin-6-as-Common-Critical-Dysregulated-Proteins-Between-Migraine-and-Gliosarcoma
Introduction It is reported that migraine may be a risk factor for brain cancers. Since one of the best ways to assess this possible relationship is to study the molecular mechanism, here the common central dysregulated proteins between these diseases are investigated via network analysis. Abstract Introduction It is reported that migraine may be a risk factor for brain cancers. Since one of the best ways to assess this possible relationship is to study the molecular mechanism, here the common c
Network analysis of liver cancer: a system biology approach
https://ctrmrc.tums.ac.ir//مقالات-علمی/Network-analysis-of-liver-cancer:-a-system-biology-approach
Aim Determining critical dysregulated proteins in liver cancer was the main aim of this study Abstract Aim Determining critical dysregulated proteins in liver cancer was the main aim of this study. Background Liver cancer is a common health problem characterized by difficulties in early diagnosis and rapid progression. Due to the lack of targeted drugs and the other features of the disease, the survival rate for patients is extremely low. Methods The related dysregulated proteins for liver cance
